CLINICAL CASE: RARE COURSE OF JUVENILE SCLERODERMA IN RESIDENTS OF DONETSK REGION

The article presents a clinical case of rare onset and special course juvenile scleroderma. A child who was born lives in the ecologically unfavorable industrial Donetsk region is described. literature review influence environment on morbidity features autoimmune pathology patients offered. In particular, indicates that negative environmental factors lead to an increase progression systemic scleroderma; over past 20 years, there has been tendency increased mortality children suffering from it, which associated with deteriorating conditions regions. growing incidence prevalence scleroderma, variety manifestations, difficulties early diagnosis disease make it important study options for this adolescents stages disease. feature scleroderma severe convulsive syndrome at age 8 required Finlepsin dose 200 mg daily. Further also uncharacteristic: within 2 linear indentation forehead right side; patient diagnosed "saber-shaped" limited Parry–Romberg facial hemiatrophy syndrome, further developed manifestations involvement, lesions internal organs: pneumofibrosis esophagitis. management observation are presented here. It emphasized aggressive intervention led prevention organ death. described expands knowledge physicians polymorphism disease, allows faster more accurate identification timely adequate therapy, will earlier stabilization remission